Fetal Calf Serum (FCS, also known as Fetal Bovine Serum, or FBS) is a common supplement of animal cell culture media. However, FCS is harvested, with a high chance of suffering, from bovine fetuses taken from pregnant cows during slaughter. Furthermore, since it is a natural product, the composition of the commercially available FCS varies from batch to batch, which impedes the reproducibility of results. These moral and scientific concerns demonstrate the urgency to switch to an FCS-free medium. The FCS-free Database provides an overview of the range of commercially available FCS-free media for cell-culture, as well as medium compositions obtained from scientific literature. Additionally, the forum function allows researchers to discuss on the applicability of each product. The database is offered by the 3Rs-Centre ULS in collaboration with Animal Free Research UK.

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How to use this website

You have free access to the entire database. Choose between the different cell types, products, sources (i.e. companies or literature), and specified parameters and compare these with each other in order to choose the best medium for your research.

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