Fetal Calf Serum (FCS, also known as Fetal Bovine Serum, or FBS) is a common supplement of animal cell culture media. However, moral and scientific concerns demonstrate the urgency to switch to an FCS-free medium. The FCS-free Database (RRID:SCR_018769), part of the 3Rs Database Programme, provides an overview of FCS-free media for cell-culture. A forum function for each record allows researchers to discuss the applicability of each product. The database is offered by the 3Rs-Centre ULS in collaboration with Animal Free Research UK.

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How to use this website

You have free access to the entire database. Choose between the different cell types, products, sources (i.e. companies or literature), and specified parameters and compare these with each other in order to choose the best medium for your research.

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