Cell line/type | CHO (Chinese Hamster Ovary) DG44 |
---|---|
Species | Hamster |
Animal free | Unspecified |
Product | CDM4CHO, HyCellCHO, ActiPro, Kim et al. 2020 |
Kim, Y.J., Han, S.K., Yoon, S. et al. Rich production media as a platform for CHO cell line development. AMB Expr10, 93 (2020). https://doi.org/10.1186/s13568-020-01025-3 Mested:;CDM4CHO, HyCellCHO, ActivPro Connclusion: Herein, we demonstrated that recent rich commercial CHO media formulated for production can be applied as basal media for CLD, serving the cell growth in the initial host cell, screening and selection after transfection, and final production. Developed methods may remove the requirements for cell adaptation to production media after CLD and relieve the clonality issues associated with changing the culture media. This practice will also decrease both time and effort, eliminating the need to adapt cells in new media and optimize the production media process. This will be highly beneficial in modern CLD approaches requiring a shorter development timeline. https://doi.org/10.1186/s13568-020-01025-3 |
|
Source | Literature - commercial |
Chemically defined > Yes | Yes |
Kim 2020 - Kim, Y.J., Han, S.K., Yoon, S. et al. Rich production media as a platform for CHO cell line development. AMB Expr 10, 93 (2020). https://doi.org/10.1186/s13568-020-01025-3 |