Cell line/type | CHO (Chinese Hamster Ovary) CHO-K1 |
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Species | Hamster |
Animal free | Yes |
Product | EX-CELL/CDM4CHO |
Rodrigues, M. E., Costa, A. R., Henriques, M., Azeredo, J., & Oliveira, R. (2012). Comparison of commercial serum-free media for CHO-K1 cell growth and monoclonal antibody production. International journal of pharmaceutics, 437(1-2), 303-305. In this study, seven commercially available serum-free media (EX-CELL, ISF-I, CD CHO, CDM4CHO, CHO-III-A, Octomed and HybridoMed) were evaluated and compared for cell growth and monoclonal antibody (mAb) production of a transfected CHO-K1 cell line. In the conditions assayed, EX-CELL and particularly CDM4CHO are the most recommended media for extended biopharmaceutical processes, on account of inducing superior levels of cell proliferation and mAb production, accentuated by a tendency to improve over time. EX-CELL and CDM4CHO are commercially available products. Their formulation is proprietary. https://ac.els-cdn.com/S037851731200796X/1-s2.0-S037851731200796X-main.pdf?_tid=5905e405-53f2-4aa5-a2da-7bc863b3fdce&acdnat=1533545796_5c0883a6ec7556ae57599e59d2af1799 |
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Source | Literature - commercial |
Chemically defined > Yes | Yes |