Cell line/type | MSCs (mesenchymal stem cells) |
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Species | Human |
Animal free | Yes |
Product | STK2 Ishikawa et al. 2009 |
Ishikawa, I., Sawada, R., Kato, Y., Tsuji, K., Shao, J., Yamada, T., ... & Tsuchiya, T. (2009). Effectivity of the novel serum-free medium STK2 for proliferating human mesenchymal stem cells. Yakugaku zasshi: Journal of the Pharmaceutical Society of Japan, 129(3), 381-384. In this study, the authors cultured hMSC with three kinds of medium used for multiplying hMSC (DMEM, MSCGM, STK2) and compared hMSC proliferation in each medium. As a result, it was confirmed that hMSC proliferation was significantly higher in STK2 medium which is a novel serum-free medium developed for hMSC multiplication. Moreover, we compared the hMSC proliferation in these media under the environment that assumed bone reproduction. When we cultured hMSC in each medium with hydroxyapatite (HAp), the proliferative inhibition by HAp depended on the additive amount, and the degree of the proliferative inhibition was different among the media but the lowest inhibitory effect was observed in STK2 medium. The precise formulation of STK2 medium is proprietary. https://www.jstage.jst.go.jp/article/yakushi/129/3/129_3_381/_pdf |
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Source | Literature - commercial |
Chemically defined > Yes | Yes |