|Cell line/type||Vero cells|
|Species||African green monkey|
|Product||VP-SFM Kurokawa et al. 2011|
Kurokawa, M., & Sato, S. (2011). Growth and poliovirus production of Vero cells on a novel microcarrier with artificial cell adhesive protein under serum-free conditions. Journal of bioscience and bioengineering, 111(5), 600-604.
In this study, serumfree culture of Vero cells for vaccine production using the microcarrier increased the number of Vero cells by approximately 30% compared with the existing dextran beads coated with porcine Type I collagen, which resulted in approximately a 30% to 40% increase in the infectivity titer of the Sabin 2 strain of poliovirus. These results suggested that the developed microcarrier should be unprecedented in permitting high-yield vaccine production by means of a serum-free culture.
VP-SFM is a serum-free, ultra-low protein (5 µg/ml) medium containing no proteins, peptides, or other components of animal or human origin. VP-SFM is a commercially available product. The precise formulation is proprietary.https://ac.els-cdn.com/S1389172310004226/1-s2.0-S1389172310004226-main.pdf?_tid=b0825df4-3793-4653-bf21-7c43e0d6b33c&acdnat=1533637361_61a4e778d0e26a9f3af917bc851658fe
|Source||Literature - commercial|
|Chemically defined > Unspecified||Unspecified|
|Contains phenol red > Yes||Yes|
|Antibiotics free > Yes||Yes|