Cell line/type | CHO (Chinese Hamster Ovary) cell line |
---|---|
Species | Hamster |
Animal free | Yes |
Product | ProCHO4 Astley et al. 2008 |
Astley, K., & Al-Rubeai, M. (2008). The role of Bcl-2 and its combined effect with p21 CIP1 in adaptation of CHO cells to suspension and protein-free culture. Applied microbiology and biotechnology, 78(3), 391-399. In this study, to determine if the overexpression of Bcl-2 could improve the process of adaptation to suspension and protein-free growth environments, the growth and viability of anchorage-dependent Chinese hamster ovary cell lines that differ only in their expression of Bcl-2 were studied. The effect of combining Bcl-2 and p21CIP1 expression during adaptation to suspension and protein-free environments was examined. A potential role for Bcl-2 in the process of adaptation of industrially important cell lines to chemically defined growth environments was identified. ProCHO4 is a commercially available protein-free medium. The precise formulation is proprietary. https://link.springer.com/content/pdf/10.1007%2Fs00253-007-1320-2.pdf |
|
Source | Literature - commercial |
Chemically defined > Yes | Yes |
Contains phenol red > No | No |
Antibiotics free > Unspecified | Unspecified |