|Cell line/type||DCs (dendritic cells)|
|Product||CellGro DC medium|
Röner, S., Zinser, E., Menges, M., Wiethe, C., Littmann, L., Hänig, J., ... & Lutz, M. B. (2008). Minor role of bystander tolerance to fetal calf serum in a peptide-specific dendritic cell vaccine model against autoimmunity: comparison with serum-free cultures. Journal of Immunotherapy, 31(7), 656-664.
In this study, the role of FCS in an autoimmune model where dendritic cells (DCs) injections can prevent peptide-specifically from experimental autoimmune encephalomyelitis (EAE) was investigated. Murine bone marrow-derived DCs generated in FCS-containing or serum-free media resulting in a similar phenotype, maturation potential, and functions. Peptide-specific protection could be achieved similarly with FCS-DC or serum-free DCs.
DCs were generated from BM precursors of mice in serum-free CellGro DC medium. CellGro DC is a commercially available product. The precise formulation is proprietary.https://journals.lww.com/immunotherapy-journal/fulltext/2008/09000/Minor_Role_of_Bystander_Tolerance_to_Fetal_Calf.6.aspx
|Source||Literature - commercial|
|Chemically defined > Yes||Yes|