Cell line/type | Endometrial organoids |
---|---|
Species | Human |
Animal free | Yes |
Product | ExM |
Turco, M. Y., Gardner, L., Hughes, J., Cindrova-Davies, T., Gomez, M. J., Farrell, L., ... & Simons, B. D. (2017). Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium. Nature cell biology, 19(5), 568. In this study, a three-dimensional cultures of normal and decidualized human endometrium was created. These organoids expand long-term, are genetically stable and differentiate following treatment with reproductive hormones. Single cells from both endometrium and decidua can generate a fully functional organoid. Long-term, chemically defined 3D glandular organoid cultures from non-pregnant endometrium and decidua were generated. In this study, the expansion medium (ExM), gave the highest yield of organoids The precise formula of ExM medium is listed in the Supplementary Information in Table S3: Expansion medium (ExM) composition for the culture of organoids from human endometrium. https://www.nature.com/articles/ncb3516.pdf |
|
Source | Literature - own formulation |
Chemically defined > Yes | Yes |
Contains phenol red > Yes | Yes |
Antibiotics free > Yes | Yes |